Product Profile

Product Name	COX2 antibody (ready-to-use)
Antibody Type	Primary Antibodies
Product description	Rabbit polyclonal to COX2 / Cyclooxygenase 2 predilutedCOX2 (Cyclooxygenase 2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged. Hide
Immunogen	Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Rat) (C terminal).

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	IHC-P
	IHC-P: Use neat for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity	Human
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Synonyms	29527 COX-2 Cox2 Ptgs2 COX 2 Hide
Target	COX2
Cellular Localization	Microsomal membrane

Application

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Application

Human Breast Carcinoma stained with anti-COX-2 antibody

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Application

staining COX2 / Cyclooxygenase in human breast carcinoma by Immunohistochemistry (FFPE-sections).

Positive Control	Lung carcinoma ,colon carcinoma
Application Notes	IHC-P: Use neat for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the end user.:

Additional Information

Form	Liquid
Storage Instructions	Keep as concentrated solution and store at 4°C. Do not freeze.
Storage Buffer	PBS, pH 7.4 containing 1%BSA and 0.1% sodium azide