产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-FLT3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
FLT3
Gene Synonyms
FLK2
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Gene Full Name
fms related receptor tyrosine kinase 3
Gene Summary
This gene encodes a class III receptor
tyrosine kinase that regulates hematopoiesis. This receptor is activated by
binding of the fms-related tyrosine kinase 3 ligand to the extracellular
domain, which induces homodimer formation in the plasma membrane leading to
autophosphorylation of the receptor. The activated receptor kinase
subsequently phosphorylates and activates multiple cytoplasmic effector
molecules in pathways involved in apoptosis, proliferation, and
differentiation of hematopoietic cells in bone marrow. Mutations that result
in the constitutive activation of this receptor result in acute myeloid
leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]
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Molecular
Weight(MW)
113KD
Cellular
Localizatio
Endoplasmic reticulum
Application
ICC/IF:1:100-1:500
STK1
CD135
FLK-2
·
IHC
Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using FLT3 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using FLT3 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using FLT3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
IHC:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |