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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-WHSC2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
NELFA
Gene Synonyms
WHSC2
Gene Full Name
negative elongation factor complex member
A
Gene Summary
This gene is expressed ubiquitously with
higher levels in fetal than in adult tissues. It encodes a protein sharing
93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS)
is a malformation syndrome associated with a hemizygous deletion of the
distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS
critical region, and may play a role in the phenotype of the WHS or
Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of
reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes,
suggesting a target for use in specific immunotherapy for a large number of
cancer patients. This protein has also been shown to be a member of the NELF (negative
elongation factor) protein complex that participates in the regulation of RNA
polymerase II transcription elongation. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
57KD
Cellular
Localizatio
Nucleus
Application
IHC:1:200-1:2000
NELF-A
P/OKcl.15
·
WB
Western blot analysis using WHSC2 antibody against A549(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using WHSC2 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using WHSC2 antibody with DAB staining.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |