产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-RAP1A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
RAP1A
Gene Synonyms
RAP1
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Gene Full Name
RAP1A, member of RAS oncogene family
Gene Summary
This gene encodes a member of the Ras
family of small GTPases. The encoded protein undergoes a change in
conformational state and activity, depending on whether it is bound to GTP or
GDP. This protein is activated by several types of guanine nucleotide exchange
factors (GEFs), and inactivated by two groups of GTPase-activating proteins
(GAPs). The activation status of the encoded protein is therefore affected by
the balance of intracellular levels of GEFs and GAPs. The encoded protein
regulates signaling pathways that affect cell proliferation and adhesion, and
may play a role in tumor malignancy. Pseudogenes of this gene have been
defined on chromosomes 14 and 17. Alternative splicing results in multiple
transcript variants. [provided by RefSeq, May 2014]
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Molecular
Weight(MW)
21KD
Cellular
Localizatio
Cell junction, Cell membrane, Cytoplasm,
Endosome, Membrane
Application
IHC:1:200-1:2000
ICC/IF:1:100-1:500
C21KG
G-22K
KREV1
KREV-1
SMGP21
·
WB
Western blot analysis using RAP1A antibody against Hek293(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded liver cancer tissues using RAP1A antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using RAP1A antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |