产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-ALPL antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
ALPL
Gene Synonyms
HOPS
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Gene Full Name
alkaline phosphatase, biomineralization
associated
Gene Summary
This gene encodes a member of the
alkaline phosphatase family of proteins. There are at least four distinct but
related alkaline phosphatases: intestinal, placental, placental-like, and
liver/bone/kidney (tissue non-specific). The first three are located together
on chromosome 2, while the tissue non-specific form is located on chromosome
1. The product of this gene is a membrane bound glycosylated enzyme that is
not expressed in any particular tissue and is, therefore, referred to as the
tissue-nonspecific form of the enzyme. Alternative splicing results in
multiple transcript variants, at least one of which encodes a preproprotein
that is proteolytically processed to generate the mature enzyme. This enzyme
may play a role in bone mineralization. Mutations in this gene have been
linked to hypophosphatasia, a disorder that is characterized by hypercalcemia
and skeletal defects. [provided by RefSeq, Oct 2015]
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Molecular
Weight(MW)
57 kD(Observed:110 kD)
Cellular
Localizatio
Cell membrane, Membrane, Mitochondrion
Application
ICC/IF:1:100-1:500
HPPA
HPPC
HPPI
HPPO
TNAP
TNALP
APTNAP
TNSALP
AP-TNAP
TNS-ALP
·
WB
Western blot analysis using ALPL antibody against A549(1),Hela (2),A431(3) cell lysate.
·
ICC/IF
Immunofluorescence analysis of Hela cells using ALPL antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |