产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-TNNI2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
TNNI2
Gene Synonyms
DA2B
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Gene Full Name
troponin I2, fast skeletal type
Gene Summary
This gene encodes a fast-twitch skeletal
muscle protein, a member of the troponin I gene family, and a component of
the troponin complex including troponin T, troponin C and troponin I
subunits. The troponin complex, along with tropomyosin, is responsible for
the calcium-dependent regulation of striated muscle contraction. Mouse
studies show that this component is also present in vascular smooth muscle and
may play a role in regulation of smooth muscle function. In addition to
muscle tissues, this protein is found in corneal epithelium, cartilage where
it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis,
and mammary gland where it functions as a co-activator of estrogen
receptor-related receptor alpha. This protein also suppresses tumor growth in
human ovarian carcinoma. Mutations in this gene cause myopathy and distal
arthrogryposis type 2B. Alternatively spliced transcript variants have been
found for this gene. [provided by RefSeq, Mar 2009]
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Molecular
Weight(MW)
21KD
Cellular
Localizatio
Nucleus,Cytosol, Cytoskeleton
Application
IHC:1:200-1:2000
ICC/IF:1:100-1:500
FSSV
DA2B1
fsTnI
AMCD2B
·
WB
Western blot analysis using TNNI2 antibody against HepG2(1), Hek293(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using TNNI2 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of C2C12 cells using TNNI2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |