产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-BMI1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
BMI1
Gene Synonyms
PCGF4
Hide
Gene Full Name
BMI1 proto-oncogene, polycomb ring finger
Gene Summary
This gene encodes a ring finger protein
that is major component of the polycomb group complex 1 (PRC1). This complex
functions through chromatin remodeling as an essential epigenetic repressor
of multiple regulatory genes involved in embryonic development and
self-renewal in somatic stem cells. This protein also plays a central role in
DNA damage repair. This gene is an oncogene and aberrant expression is
associated with numerous cancers and is associated with resistance to certain
chemotherapies. A pseudogene of this gene is found on chromosome X.
Read-through transcription also exists between this gene and the upstream
COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015]
Hide
Molecular
Weight(MW)
37KD
Cellular
Localizatio
Cytoplasm, Nucleus
Application
IHC:1:200-1:2000
ICC/IF:1:100-1:500
RNF51
FLVI2/BMI1
flvi-2/bmi-1
·
WB
Western blot analysis using BMI1 antibody against HepG2(1), A431(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded liver cancer tissues using BMI1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using BMI1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |