产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-PPP1CA antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PPP1CA
Gene Synonyms
PP1A
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Gene Full Name
protein phosphatase 1 catalytic subunit
alpha
Gene Summary
The protein encoded by this gene is one
of the three catalytic subunits of protein phosphatase 1 (PP1). This broadly
expressed gene encodes the alpha subunit of the PP1 complex that associates
with over 200 regulatory proteins to form holoenzymes which dephosphorylate
their biological targets with high specificity. PP1 is a serine/threonine
specific protein phosphatase known to be involved in the regulation of a
variety of cellular processes, such as cell division, glycogen metabolism,
muscle contractility, protein synthesis, and HIV-1 viral transcription.
Increased PP1 activity has been observed in the end stage of heart failure.
Studies suggest that PP1 is an important regulator of cardiac function and
that PP1 deregulation is implicated in diabetes and multiple types of cancer.
Three alternatively spliced transcript variants encoding different isoforms
have been found for this gene. [provided by RefSeq, Jul 2020]
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Molecular
Weight(MW)
38KD
Cellular
Localizatio
Cytoplasm, Nucleus
Application
ICC/IF:1:100-1:500
PP-1A
PPP1A
PP1alpha
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using PPP1CA antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using PPP1CA antibody with DAB staining.
·
ICC/F
Immunofluorescence analysis of A549 cells using PPP1CA antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
IHC:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |