产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-MBP antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ICC/IFWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
MBP
Gene Full Name
myelin basic protein
Gene Summary
The protein encoded by the classic MBP
gene is a major constituent of the myelin sheath of oligodendrocytes and
Schwann cells in the nervous system. However, MBP-related transcripts are
also present in the bone marrow and the immune system. These mRNAs arise from
the long MBP gene (otherwise called "Golli-MBP") that contains 3
additional exons located upstream of the classic MBP exons. Alternative
splicing from the Golli and the MBP transcription start sites gives rise to 2
sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3
exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They
encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP
aa sequence. The second family of transcripts contain only MBP exons and
produce the well characterized myelin basic proteins. This complex gene
structure is conserved among species suggesting that the MBP transcription
unit is an integral part of the Golli transcription unit and that this
arrangement is important for the function and/or regulation of these genes.
[provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
33kD(Observed:55 kD)
Cellular
Localizatio
Cell membrane, Membrane, Nucleus
Application
ICC/IF:1:100-1:500
·
WB
Western blot analysis using MBP antibody against NIH3T3(1) cell lysate.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using MBP antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |