产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-LRP5 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LRP5
Gene Synonyms
HBM
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Gene Full Name
LDL receptor related protein 5
Gene Summary
This gene encodes a transmembrane
low-density lipoprotein receptor that binds and internalizes ligands in the
process of receptor-mediated endocytosis. This protein also acts as a
co-receptor with Frizzled protein family members for transducing signals by
Wnt proteins and was originally cloned on the basis of its association with
type 1 diabetes mellitus in humans. This protein plays a key role in skeletal
homeostasis and many bone density related diseases are caused by mutations in
this gene. Mutations in this gene also cause familial exudative
vitreoretinopathy. Alternative splicing results in multiple transcript
variants. [provided by RefSeq, May 2014]
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Molecular
Weight(MW)
180KD
Cellular
Localizatio
Endoplasmic reticulum
Application
ICC/IF:1:100-1:500
LR3
OPS
EVR1
EVR4
LRP7
OPPG
BMND1
LRP-5
LRP-7
OPTA1
PCLD4
VBCH2
·
IHC
Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using LRP5 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using LRP5 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using LRP5 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
IHC:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |