产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-SKP1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
SKP1
Gene Synonyms
OCP2
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Gene Full Name
S-phase kinase associated protein 1
Gene Summary
This gene encodes a component of SCF
complexes, which are composed of this protein, cullin 1, a ring-box protein,
and one member of the F-box family of proteins. This protein binds directly
to the F-box motif found in F-box proteins. SCF complexes are involved in the
regulated ubiquitination of specific protein substrates, which targets them
for degradation by the proteosome. Specific F-box proteins recognize
different target protein(s), and many specific SCF substrates have been
identified including regulators of cell cycle progression and development.
Studies have also characterized the protein as an RNA polymerase II
elongation factor. Alternative splicing of this gene results in two
transcript variants. A related pseudogene has been identified on chromosome
7. [provided by RefSeq, Jul 2008]
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Molecular
Weight(MW)
19KD
Cellular
Localizatio
Nucleus,Cytosol,Cytoskeleton
Application
ICC/IF:1:100-1:500
p19A
EMC19
SKP1A
OCP-II
TCEB1L
·
IHC
Immunohistochemical analysis of paraffin-embedded liver cancer tissues using SKP1 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using SKP1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using SKP1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
IHC:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |