产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-CYP1A1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CYP1A1
Gene Synonyms
AHH
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Gene Full Name
cytochrome P450 family 1 subfamily A
member 1
Gene Summary
This gene, CYP1A1, encodes a member of
the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug metabolism and
synthesis of cholesterol, steroids and other lipids. This protein localizes
to the endoplasmic reticulum and its expression is induced by some polycyclic
aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The
enzyme's endogenous substrate is unknown; however, it is able to metabolize
some PAHs to carcinogenic intermediates. The gene has been associated with
lung cancer risk. A related family member, CYP1A2, is located approximately
25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in
multiple transcript variants encoding distinct isoforms. [provided by RefSeq,
Jan 2016]
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Molecular
Weight(MW)
58KD
Cellular
Localizatio
Cytoplasm, Endoplasmic reticulum,
Membrane, Microsome, Mitochondrion, Mitochondrion inner membrane
Application
IHC:1:200-1:200
AHRR
CP11
CYP1
CYPIA1
P1-450
P450-C
P450DX
·
WB
Western blot analysis using CYP1A1 antibody against HepG2(1), Hela(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using CYP1A1 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using CYP1A1 antibody with DAB staining.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |