|
- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：OM641708
- 发布日期： 2024-09-11
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
· 
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
FHC
FHCL1
LDLCQ2
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-LDLR antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IF
IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LDLR
Gene Synonyms
FH
Hide
Gene Full Name
low density lipoprotein receptor
Gene Summary
The low density lipoprotein receptor
(LDLR) gene family consists of cell surface proteins involved in
receptor-mediated endocytosis of specific ligands. The encoded protein is
normally bound at the cell membrane, where it binds low density
lipoprotein/cholesterol and is taken into the cell. Lysosomes release the
cholesterol, which is made available for repression of microsomal enzyme
3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting
step in cholesterol synthesis. At the same time, a reciprocal stimulation of
cholesterol ester synthesis takes place. Mutations in this gene cause the
autosomal dominant disorder, familial hypercholesterolemia. Alternate
splicing results in multiple transcript variants.[provided by RefSeq, May
2022]
Hide
Molecular
Weight(MW)
95KD
Cellular
Localizatio
Cell membrane. Endomembrane system.
Application
FHC
FHCL1
LDLCQ2
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using LDLR antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
IF:1:100-1:500 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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