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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-LMNA antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
LMNA
Gene Synonyms
FPL
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Gene Full Name
lamin A/C
Gene Summary
The protein encoded by this gene is part
of the nuclear lamina, a two-dimensional matrix of proteins located next to
the inner nuclear membrane. The lamin family of proteins make up the matrix
and are highly conserved in evolution. During mitosis, the lamina matrix is
reversibly disassembled as the lamin proteins are phosphorylated. Lamin
proteins are thought to be involved in nuclear stability, chromatin structure
and gene expression. Vertebrate lamins consist of two types, A and B.
Alternative splicing results in multiple transcript variants. Mutations in
this gene lead to several diseases: Emery-Dreifuss muscular dystrophy,
familial partial lipodystrophy, limb girdle muscular dystrophy, dilated
cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria
syndrome. [provided by RefSeq, May 2022]
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Molecular
Weight(MW)
74KD
Cellular
Localizatio
Intermediate filament, Nucleus
Application
IHC:1:200-1:2000
ICC/IF:1:100-1:500
IDC
LFP
CDDC
EMD2
FPLD
HGPS
LDP1
LMN1
LMNC
MADA
PRO1
CDCD1
CMD1A
FPLD2
LMNL1
CMT2B1
LGMD1B
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WB
Western blot analysis using LMNA antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded colon cancer tissues tissues using LMNA antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of C2C12 cells using LMNA antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |