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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-CRKL antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CRKL
Gene Full Name
CRK like proto-oncogene, adaptor protein
Gene Summary
This gene encodes a protein kinase
containing SH2 and SH3 (src homology) domains which has been shown to
activate the RAS and JUN kinase signaling pathways and transform fibroblasts
in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase,
plays a role in fibroblast transformation by BCR-ABL, and may be
oncogenic.[provided by RefSeq, Jan 2009]
Hide
Molecular
Weight(MW)
34kD(Observed 50 kD)
Cellular
Localizatio
Cytosol; Nucleus; Plasma Membrane
Application
IHC:1:200-1:2000
ICC/IF:1:100-1:500
·
WB
Western blot analysis using CRKL antibody against HepG2(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using CRKL antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using CRKL antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |