![]() |
产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-MAP2K4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
MAP2K4
Gene Synonyms
JNKK
Hide
Gene Full Name
mitogen-activated protein kinase kinase 4
Gene Summary
This gene encodes a member of the
mitogen-activated protein kinase (MAPK) family. Members of this family act as
an integration point for multiple biochemical signals and are involved in a
wide variety of cellular processes such as proliferation, differentiation,
transcription regulation, and development. They form a three-tiered signaling
module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated
at serine and threonine residues by MAPKKKs and subsequently phosphorylates
downstream MAPK targets at threonine and tyrosine residues. A similar protein
in mouse has been reported to play a role in liver organogenesis. A
pseudogene of this gene is located on the long arm of chromosome X.
Alternative splicing results in multiple transcript variants. [provided by
RefSeq, Jul 2013]
Hide
Molecular
Weight(MW)
44KD
Cellular
Localizatio
Cytoplasm, Nucleus
Application
ICC/IF:1:100-1:500
MEK4
MKK4
SEK1
SKK1
JNKK1
SERK1
MAPKK4
PRKMK4
SAPKK1
SAPKK-1
·
IHC
Immunohistochemical analysis of paraffin-embedded colon cancer tissues using MAP2K4 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded renal carcinoma tissues using MAP2K4 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using MAP2K4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
IHC:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |