Product Profile

Product Name	Anti-MAP2K6 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1mg/ml
Purification	Protein A

Target Information

Gene Symbol	MAP2K6
Gene Synonyms	MEK6 MKK6 MAPKK6 PRKMK6 SAPKK3 SAPKK-3 Hide
Gene Full Name	mitogen-activated protein kinase kinase 6
Gene Summary	This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	37KD
Cellular Localizatio	Cytoplasm, Cytoskeleton, Nucleus

Application

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WB

Western blot analysis using MAP2K6 antibody against Hela(1) cell lysate.

·       

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using MAP2K6 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of NIH3T3 cells using MAP2K6 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.