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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-ATF2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
ATF2
Gene Synonyms
HB16
More
Gene Full Name
activating transcription factor 2
Gene Summary
This gene encodes a transcription factor
that is a member of the leucine zipper family of DNA binding proteins. The
encoded protein has been identified as a moonlighting protein based on its
ability to perform mechanistically distinct functions This protein binds to
the cAMP-responsive element (CRE), an octameric palindrome. It forms a
homodimer or a heterodimer with c-Jun and stimulates CRE-dependent
transcription. This protein is also a histone acetyltransferase (HAT) that
specifically acetylates histones H2B and H4 in vitro; thus it may represent a
class of sequence-specific factors that activate transcription by direct
effects on chromatin components. The encoded protein may also be involved in
cell's DNA damage response independent of its role in transcriptional
regulation. Several alternatively spliced transcript variants have been found
for this gene [provided by RefSeq, Jan 2014]
More
Molecular
Weight(MW)
55KD
Cellular
Localizatio
Cytoplasm, Membrane, Mitochondrion,
Mitochondrion outer membrane, Nucleus
Application
IHC:1:200-1:2000
ICC/IF:1:100-1:500
CREB2
TREB7
CREB-2
CRE-BP1
·
WB
Western blot analysis using ATF2 antibody against A549(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using ATF2 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using ATF2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |