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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-CRTC2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CRTC2
Gene Synonyms
TORC2
Gene Full Name
CREB regulated transcription coactivator
2
Gene Summary
This gene encodes a member of the
transducers of regulated cAMP response element-binding protein activity
family of transcription coactivators. These proteins promote the
transcription of genes targeted by the cAMP response element-binding protein,
and therefore play an important role in many cellular processes. Under basal
conditions the encoded protein is phosphorylated by AMP-activated protein
kinase or the salt-inducible kinases and is sequestered in the cytoplasm.
Upon activation by elevated cAMP or calcium, the encoded protein translocates
to the nucleus and increases target gene expression. Single nucleotide
polymorphisms in this gene may increase the risk of type 2 diabetes. A
pseudogene of this gene is located on the long arm of chromosome 5. [provided
by RefSeq, Dec 2010]
More
Molecular
Weight(MW)
73KD
Cellular
Localizatio
Cytoplasm, Nucleus
Application
ICC/IF:1:100-1:500
TORC-2
·
IHC
Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using CRTC2 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using CRTC2 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using CRTC2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
IHC:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |