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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-CSK antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CSK
Gene Full Name
C-terminal Src kinase
Gene Summary
The protein encoded by this gene is
involved in multiple pathways, including the regulation of Src family
kinases. It plays an important role in T-cell activation through its
association with the protein encoded by the protein tyrosine phosphatase,
non-receptor type 22 (PTPN22) gene. This protein also phosphorylates
C-terminal tyrosine residues on multiple substrates, including the protein
encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene.
Phosphorylation suppresses the kinase activity of the Src family tyrosine
kinases. An intronic polymorphism (rs34933034) in this gene has been found to
affect B-cell activation and is associated with systemic lupus erythematosus
(SLE). Alternative splicing results in multiple transcript variants. [provided
by RefSeq, Aug 2017]
Hide
Molecular
Weight(MW)
51KD
Cellular
Localizatio
Cell membrane, Cytoplasm, Membrane
Application
IHC:1:200-1:2000
ICC/IF:1:100-1:500
·
WB
Western blot analysis using CSK antibody against Cos7(1), A549(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using CSK antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using CSK antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |