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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-GFI1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
GFI1
Gene Synonyms
SCN2
More
Gene Full Name
growth factor independent 1
transcriptional repressor
Gene Summary
This gene encodes a nuclear zinc finger
protein that functions as a transcriptional repressor. This protein plays a
role in diverse developmental contexts, including hematopoiesis and
oncogenesis. It functions as part of a complex along with other cofactors to
control histone modifications that lead to silencing of the target gene
promoters. Mutations in this gene cause autosomal dominant severe congenital
neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of
adults, which are heterogeneous hematopoietic disorders that cause
predispositions to leukemias and infections. Multiple alternatively spliced
variants, encoding the same protein, have been identified for this gene.
[provided by RefSeq, Jul 2008]
More
Molecular
Weight(MW)
45KD
Cellular
Localizatio
Nucleus
Application
IHC:1:200-1:2000
GFI-1
GFI1A
ZNF163
·
WB
Western blot analysis using GFI1 antibody against A431(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lymphoma tissues using GFI1 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using GFI1 antibody with DAB staining.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |