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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-TRIB2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
TRIB2
Gene Synonyms
C5FW
Gene Full Name
tribbles pseudokinase 2
Gene Summary
This gene encodes one of three members of
the Tribbles family. The Tribbles members share a Trb domain, which is
homologous to protein serine-threonine kinases, but lacks the active site
lysine and probably lacks a catalytic function. The Tribbles proteins
interact and modulate the activity of signal transduction pathways in a
number of physiological and pathological processes. This Tribbles member
induces apoptosis of cells mainly of the hematopoietic origin. It has been
identified as a protein up-regulated by inflammatory stimuli in myeloid
(THP-1) cells, and also as an oncogene that inactivates the transcription
factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute
myelogenous leukemia. Alternatively spliced transcript variants have been
found for this gene. [provided by RefSeq, Mar 2009]
Hide
Molecular
Weight(MW)
39kD(Observed:55kD)
Cellular
Localizatio
Cytoplasm, Cytoskeleton
Application
IHC:1:200-1:2000
ICC/IF:1:100-1:500
TRB2
GS3955
·
WB
Western blot analysis using TRIB2 antibody against Hela(1), MCF-7(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded renal carcinoma tissues using TRIB2 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using TRIB2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |