![]() |
产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-STAT5B antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
STAT5B
Gene Synonyms
STAT5
Gene Full Name
signal transducer and activator of
transcription 5B
Gene Summary
The protein encoded by this gene is a
member of the STAT family of transcription factors. In response to cytokines
and growth factors, STAT family members are phosphorylated by the receptor
associated kinases, and then form homo- or heterodimers that translocate to
the cell nucleus where they act as transcription activators. This protein
mediates the signal transduction triggered by various cell ligands, such as
IL2, IL4, CSF1, and different growth hormones. It has been shown to be
involved in diverse biological processes, such as TCR signaling, apoptosis,
adult mammary gland development, and sexual dimorphism of liver gene
expression. This gene was found to fuse to retinoic acid receptor-alpha
(RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The
dysregulation of the signaling pathways mediated by this protein may be the
cause of the APLL. [provided by RefSeq, Jul 2008]
Hide
Molecular
Weight(MW)
90KD
Cellular
Localizatio
Cytoplasm, Nucleus
Application
IHC:1:200-1:2000
ICC/IF:1:100-1:500
GHISID2
·
WB
Western blot analysis using STAT5B antibody against HepG2(1), K562(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using STAT5B antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using STAT5B antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |