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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-PAX6 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PAX6
Gene Synonyms
AN
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Gene Full Name
paired box 6
Gene Summary
This gene encodes paired box protein
Pax-6, one of many human homologs of the Drosophila melanogaster gene prd. In
addition to a conserved paired box domain, a hallmark feature of this gene
family, the encoded protein also contains a homeobox domain. Both domains are
known to bind DNA and function as regulators of gene transcription. Activity
of this protein is key in the development of neural tissues, particularly the
eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases
distant from this locus. Mutations in this gene or in the enhancer regions
can cause ocular disorders such as aniridia and Peter's anomaly. Use of
alternate promoters and alternative splicing results in multiple transcript
variants encoding different isoforms. Interestingly, inclusion of a
particular alternate coding exon has been shown to increase the length of the
paired box domain and alter its DNA binding specificity. Consequently,
isoforms that carry the shorter paired box domain regulate a different set of
genes compared to the isoforms carrying the longer paired box domain.
[provided by RefSeq, Mar 2019]
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Molecular
Weight(MW)
47KD
Cellular
Localizatio
Nucleus
Application
IHC:1:200-1:2000
AN1
AN2
FVH1
MGDA
WAGR
ASGD5
D11S812E
·
WB
Western blot analysis using PAX6 antibody against Hela(1),SK-N-SH(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using PAX6 antibody with DAB staining.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |