Product Profile

Product Name	Anti-BCL6 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAWB
	WB:1:200-1:2000
Species Reactivity	HumanMouseRat
Concentration	1mg/ml
Purification	Protein A

Target Information

Gene Symbol	BCL6
Gene Synonyms	BCL5 LAZ3 BCL6A ZNF51 ZBTB27 Hide
Gene Full Name	BCL6 transcription repressor
Gene Summary	The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015] Hide
Molecular Weight(MW)	79KD
Cellular Localizatio	Nucleus

Application

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WB

Western blot analysis using BCL6 antibody against A549(1),COS7(2),MCF-7(3),NIH3T3(4) cell lysate.

Application Notes

WB:1:200-1:2000

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.