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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-CAMKK2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
CAMKK2
Gene Synonyms
CAMKK
Gene Full Name
calcium/calmodulin dependent protein
kinase kinase 2
Gene Summary
The product of this gene belongs to the
Serine/Threonine protein kinase family, and to the
Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of
this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase
cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein
products of this gene also phosphorylate AMP-activated protein kinase (AMPK).
This gene has its strongest expression in the brain and influences signalling
cascades involved with learning and memory, neuronal differentiation and
migration, neurite outgrowth, and synapse formation. Alternative splicing
results in multiple transcript variants encoding distinct isoforms. The
identified isoforms differ in their ability to undergo autophosphorylation and
to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]
Hide
Molecular
Weight(MW)
65KD
Cellular
Localizatio
Cell projection, Cytoplasm, Nucleus
Application
IHC:1:200-1:2000
ICC/IF:1:100-1:500
CAMKKB
·
WB
Western blot analysis using CAMKK2 antibody against PC-12(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using CAMKK2 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of PC-3 cells using CAMKK2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |