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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-EPO antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
EPO
Gene Synonyms
EP
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Gene Full Name
erythropoietin
Gene Summary
This gene encodes a secreted,
glycosylated cytokine composed of four alpha helical bundles. The encoded
protein is mainly synthesized in the kidney, secreted into the blood plasma,
and binds to the erythropoietin receptor to promote red blood cell
production, or erythropoiesis, in the bone marrow. Expression of this gene is
upregulated under hypoxic conditions, in turn leading to increased
erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression
of this gene has also been observed in brain and in the eye, and elevated
expression levels have been observed in diabetic retinopathy and ocular
hypertension. Recombinant forms of the encoded protein exhibit neuroprotective
activity against a variety of potential brain injuries, as well as
antiapoptotic functions in several tissue types, and have been used in the
treatment of anemia and to enhance the efficacy of cancer therapies.
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Molecular
Weight(MW)
21 kDa(Observed:33
kDa)
Cellular
Localizatio
Secreted
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
DBAL
ECYT5
MVCD2
·
WB
Western blot analysis using EPO antibody against Jurkat(1), A431(2), MCF-7(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using Interleukin 1 beta antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using EPO antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |