|
- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：电询
- 发布日期： 2024-09-09
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | 电询 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
· 
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-AKAP13 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
AKAP13
Gene Synonyms
BRX
LBC
p47
HA-3
Ht31
c-lbc
PRKA13
AKAP-13
AKAP-Lbc
ARHGEF13
PROTO-LB
PROTO-LBC
More
Gene Full Name
A-kinase anchoring protein 13
Gene Summary
The A-kinase anchor proteins (AKAPs) are
a group of structurally diverse proteins which have the common function of
binding to the regulatory subunit of protein kinase A (PKA) and confining the
holoenzyme to discrete locations within the cell. This gene encodes a member
of the AKAP family. Alternative splicing of this gene results in multiple
transcript variants encoding different isoforms containing c-terminal dbl
oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is
associated with guanine nucleotide exchange activation for the Rho/Rac family
of small GTP binding proteins, resulting in the conversion of the inactive
GTPase to the active form capable of transducing signals. The PH domain has
multiple functions. Therefore, these isoforms function as scaffolding
proteins to coordinate a Rho signaling pathway, function as protein kinase
A-anchoring proteins and, in addition, enhance ligand-dependent activity of
estrogen receptors alpha and beta.
More
Molecular
Weight(MW)
307 kDa
Cellular
Localizatio
Cytoplasm, Membrane, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
|
Product Name |
Anti-AKAP13 antibody |
|
Antibody Type |
Primary Antibodies |
|
Immunogen |
Polypeptide |
Key Feature
|
Clonality |
Polyclonal |
|
Isotype |
IgG |
|
Host Species |
Rabbit |
|
Tested Application |
ELISAICC/IFIHC |
|
IHC:1:200-1:1000 |
|
|
Species Reactivity |
HumanMouseRat |
|
Concentration |
1 mg/ml |
|
Purification |
Protein A |
Target Information
|
Gene Symbol |
AKAP13 |
|
Gene Synonyms |
BRX More |
|
Gene Full Name |
A-kinase anchoring protein 13 |
|
Gene Summary |
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. More |
|
Molecular Weight(MW) |
307 kDa |
|
Cellular Localizatio |
Cytoplasm, Membrane, Nucleus |
Application
·
IHC
Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using AKAP13 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using AKAP13 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using AKAP13 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
IHC:1:200-1:1000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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