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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-P4HB antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
P4HB
Gene Synonyms
DSI
More
Gene Full Name
prolyl 4-hydroxylase subunit beta
Gene Summary
This gene encodes the beta subunit of
prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs
to the protein disulfide isomerase family. When present as a tetramer
consisting of two alpha and two beta subunits, this enzyme is involved in
hydroxylation of prolyl residues in preprocollagen. This enzyme is also a
disulfide isomerase containing two thioredoxin domains that catalyze the
formation, breakage and rearrangement of disulfide bonds. Other known
functions include its ability to act as a chaperone that inhibits aggregation
of misfolded proteins in a concentration-dependent manner, its ability to
bind thyroid hormone, its role in both the influx and efflux of
S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal
triglyceride transfer protein complex.
More
Molecular
Weight(MW)
57 kDa
Cellular
Localizatio
Cell membrane, Endoplasmic reticulum,
Membrane
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
GIT
PDI
PHDB
PDIA1
PO4DB
PO4HB
PROHB
CLCRP1
ERBA2L
P4Hbeta
·
WB
Western blot analysis using P4HB antibody against PANC-1(1),COS7(2),MCF-7(3),NIH3T3(4)cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using P4HB antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of CAL-27 cells using P4HB antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |