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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-SOCS3 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SOCS3
Gene Synonyms
CIS3
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Gene Full Name
suppressor of cytokine signaling 3
Gene Summary
This gene encodes a member of the
STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine
signaling (SOCS), family. SSI family members are cytokine-inducible negative
regulators of cytokine signaling. The expression of this gene is induced by
various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The
protein encoded by this gene can bind to JAK2 kinase, and inhibit the
activity of JAK2 kinase. Studies of the mouse counterpart of this gene
suggested the roles of this gene in the negative regulation of fetal liver
hematopoiesis, and placental development.
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Molecular
Weight(MW)
25 kDa
Cellular
Localizatio
Cytosol
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using SOCS3 antibody with DAB
staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded stomach cancer tissues using SOCS3 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using SOCS3 antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
IHC:1:200-1:1000
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
ICC/IF:1:100-1:500
SSI3
ATOD4
Cish3
SSI-3
SOCS-3
ICC/IF:1:100-1:500