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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-CYP1A2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CYP1A2
Gene Synonyms
CP12
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Gene Full Name
cytochrome P450 family 1 subfamily A
member 2
Gene Summary
This gene encodes a member of the
cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug metabolism and
synthesis of cholesterol, steroids and other lipids. The protein encoded by
this gene localizes to the endoplasmic reticulum and its expression is
induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are
found in cigarette smoke. The enzyme's endogenous substrate is unknown;
however, it is able to metabolize some PAHs to carcinogenic intermediates.
Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1,
and acetaminophen. The transcript from this gene contains four Alu sequences
flanked by direct repeats in the 3' untranslated region.
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Molecular
Weight(MW)
58 kDa
Cellular
Localizatio
Endoplasmic reticulum, Membrane,
Microsome
Application
ICC/IF:1:100-1:500
CYPIA2
P3-450
P450(PA)
·
WB
Western blot analysis using CYP1A2 antibody against A549(1), COS7(2), NIH3T3(3)cell lysate.
·
ICC/IF
Immunofluorescence analysis of CAL-27 cells using CYP1A2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |