|
- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：OM641708
- 发布日期： 2024-09-06
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-PRKAB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKAB1
Gene Synonyms
AMPK
HAMPKb
Gene Full Name
protein kinase AMP-activated
non-catalytic subunit beta 1
Gene Summary
The protein encoded by this gene is a
regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a
heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that monitors
cellular energy status. In response to cellular metabolic stresses, AMPK is
activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase
(ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes
involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This subunit may be a positive regulator of AMPK activity. The myristoylation
and phosphorylation of this subunit have been shown to affect the enzyme
activity and cellular localization of AMPK. This subunit may also serve as an
adaptor molecule mediating the association of the AMPK complex.
More
Molecular
Weight(MW)
30 kDa
Cellular
Localizatio
Cytosol, nucleoplasm, nucleus, cytoplasm
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PRKAB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKAB1
Gene Synonyms
AMPK
HAMPKb
Gene Full Name
protein kinase AMP-activated
non-catalytic subunit beta 1
Gene Summary
The protein encoded by this gene is a
regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a
heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that monitors
cellular energy status. In response to cellular metabolic stresses, AMPK is
activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase
(ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes
involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This subunit may be a positive regulator of AMPK activity. The myristoylation
and phosphorylation of this subunit have been shown to affect the enzyme
activity and cellular localization of AMPK. This subunit may also serve as an
adaptor molecule mediating the association of the AMPK complex.
More
Molecular
Weight(MW)
30 kDa
Cellular
Localizatio
Cytosol, nucleoplasm, nucleus, cytoplasm
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PRKAB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKAB1
Gene Synonyms
AMPK
HAMPKb
Gene Full Name
protein kinase AMP-activated
non-catalytic subunit beta 1
Gene Summary
The protein encoded by this gene is a
regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a
heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that monitors
cellular energy status. In response to cellular metabolic stresses, AMPK is
activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase
(ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes
involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This subunit may be a positive regulator of AMPK activity. The myristoylation
and phosphorylation of this subunit have been shown to affect the enzyme
activity and cellular localization of AMPK. This subunit may also serve as an
adaptor molecule mediating the association of the AMPK complex.
More
Molecular
Weight(MW)
30 kDa
Cellular
Localizatio
Cytosol, nucleoplasm, nucleus, cytoplasm
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PRKAB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKAB1
Gene Synonyms
AMPK
HAMPKb
Gene Full Name
protein kinase AMP-activated
non-catalytic subunit beta 1
Gene Summary
The protein encoded by this gene is a
regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a
heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that monitors
cellular energy status. In response to cellular metabolic stresses, AMPK is
activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase
(ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes
involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This subunit may be a positive regulator of AMPK activity. The myristoylation
and phosphorylation of this subunit have been shown to affect the enzyme
activity and cellular localization of AMPK. This subunit may also serve as an
adaptor molecule mediating the association of the AMPK complex.
More
Molecular
Weight(MW)
30 kDa
Cellular
Localizatio
Cytosol, nucleoplasm, nucleus, cytoplasm
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PRKAB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKAB1
Gene Synonyms
AMPK
HAMPKb
Gene Full Name
protein kinase AMP-activated
non-catalytic subunit beta 1
Gene Summary
The protein encoded by this gene is a
regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a
heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that monitors
cellular energy status. In response to cellular metabolic stresses, AMPK is
activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase
(ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes
involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This subunit may be a positive regulator of AMPK activity. The myristoylation
and phosphorylation of this subunit have been shown to affect the enzyme
activity and cellular localization of AMPK. This subunit may also serve as an
adaptor molecule mediating the association of the AMPK complex.
More
Molecular
Weight(MW)
30 kDa
Cellular
Localizatio
Cytosol, nucleoplasm, nucleus, cytoplasm
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PRKAB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKAB1
Gene Synonyms
AMPK
HAMPKb
Gene Full Name
protein kinase AMP-activated
non-catalytic subunit beta 1
Gene Summary
The protein encoded by this gene is a
regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a
heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that monitors
cellular energy status. In response to cellular metabolic stresses, AMPK is
activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase
(ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes
involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This subunit may be a positive regulator of AMPK activity. The myristoylation
and phosphorylation of this subunit have been shown to affect the enzyme
activity and cellular localization of AMPK. This subunit may also serve as an
adaptor molecule mediating the association of the AMPK complex.
More
Molecular
Weight(MW)
30 kDa
Cellular
Localizatio
Cytosol, nucleoplasm, nucleus, cytoplasm
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PRKAB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKAB1
Gene Synonyms
AMPK
HAMPKb
Gene Full Name
protein kinase AMP-activated
non-catalytic subunit beta 1
Gene Summary
The protein encoded by this gene is a
regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a
heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that monitors
cellular energy status. In response to cellular metabolic stresses, AMPK is
activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase
(ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes
involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This subunit may be a positive regulator of AMPK activity. The myristoylation
and phosphorylation of this subunit have been shown to affect the enzyme
activity and cellular localization of AMPK. This subunit may also serve as an
adaptor molecule mediating the association of the AMPK complex.
More
Molecular
Weight(MW)
30 kDa
Cellular
Localizatio
Cytosol, nucleoplasm, nucleus, cytoplasm
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PRKAB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKAB1
Gene Synonyms
AMPK
HAMPKb
Gene Full Name
protein kinase AMP-activated
non-catalytic subunit beta 1
Gene Summary
The protein encoded by this gene is a
regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a
heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that monitors
cellular energy status. In response to cellular metabolic stresses, AMPK is
activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase
(ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes
involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This subunit may be a positive regulator of AMPK activity. The myristoylation
and phosphorylation of this subunit have been shown to affect the enzyme
activity and cellular localization of AMPK. This subunit may also serve as an
adaptor molecule mediating the association of the AMPK complex.
More
Molecular
Weight(MW)
30 kDa
Cellular
Localizatio
Cytosol, nucleoplasm, nucleus, cytoplasm
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PRKAB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKAB1
Gene Synonyms
AMPK
HAMPKb
Gene Full Name
protein kinase AMP-activated
non-catalytic subunit beta 1
Gene Summary
The protein encoded by this gene is a
regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a
heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that monitors
cellular energy status. In response to cellular metabolic stresses, AMPK is
activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase
(ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes
involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This subunit may be a positive regulator of AMPK activity. The myristoylation
and phosphorylation of this subunit have been shown to affect the enzyme
activity and cellular localization of AMPK. This subunit may also serve as an
adaptor molecule mediating the association of the AMPK complex.
More
Molecular
Weight(MW)
30 kDa
Cellular
Localizatio
Cytosol, nucleoplasm, nucleus, cytoplasm
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PRKAB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKAB1
Gene Synonyms
AMPK
HAMPKb
Gene Full Name
protein kinase AMP-activated
non-catalytic subunit beta 1
Gene Summary
The protein encoded by this gene is a
regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a
heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that monitors
cellular energy status. In response to cellular metabolic stresses, AMPK is
activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase
(ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes
involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This subunit may be a positive regulator of AMPK activity. The myristoylation
and phosphorylation of this subunit have been shown to affect the enzyme
activity and cellular localization of AMPK. This subunit may also serve as an
adaptor molecule mediating the association of the AMPK complex.
More
Molecular
Weight(MW)
30 kDa
Cellular
Localizatio
Cytosol, nucleoplasm, nucleus, cytoplasm
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with
DAB staining.
·
IHC
Immunohistochemical
analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-PRKAB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKAB1
Gene Synonyms
AMPK
Gene Full Name
protein kinase AMP-activated
non-catalytic subunit beta 1
Gene Summary
The protein encoded by this gene is a
regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a
heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that monitors
cellular energy status. In response to cellular metabolic stresses, AMPK is
activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase
(ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes
involved in regulating de novo biosynthesis of fatty acid and cholesterol.
This subunit may be a positive regulator of AMPK activity. The myristoylation
and phosphorylation of this subunit have been shown to affect the enzyme
activity and cellular localization of AMPK. This subunit may also serve as an
adaptor molecule mediating the association of the AMPK complex.
More
Molecular
Weight(MW)
30 kDa
Cellular
Localizatio
Cytosol, nucleoplasm, nucleus, cytoplasm
Application
ICC/IF:1:100-1:500
HAMPKb
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using PRKAB1 antibody with DAB staining.
·
IHC
Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using PRKAB1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using PRKAB1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
IHC:1:200-1:1000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
-
中秋迎好礼 中秋迎好礼 随着国产3A大作《黑神话：悟空》的面世，现我司推出活动。 从即日起至2024年9月18日，购买ELISA试剂盒满五盒，即可申领《黑神话：悟空》数字标准版兑换码。 ... VIEW DETAILS
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