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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-JNK2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
MAPK9
Gene Synonyms
JNK2
More
Gene Full Name
mitogen-activated protein kinase 9
Gene Summary
The protein encoded by this gene is a
member of the MAP kinase family. MAP kinases act as an integration point for
multiple biochemical signals, and are involved in a wide variety of cellular
processes such as proliferation, differentiation, transcription regulation
and development. This kinase targets specific transcription factors, and thus
mediates immediate-early gene expression in response to various cell stimuli.
It is most closely related to MAPK8, both of which are involved in UV
radiation induced apoptosis, thought to be related to the cytochrome
c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun
N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor
p53, and thus it increases the stability of p53 in nonstressed cells. Studies
of this gene's mouse counterpart suggest a key role in T-cell
differentiation. Several alternatively spliced transcript variants encoding
distinct isoforms have been reported.
More
Molecular Weight(MW)
48 kDa
Cellular
Localizatio
Cytoplasm, Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
SAPK
p54a
JNK2A
JNK2B
PRKM9
JNK-55
SAPK1a
JNK2BETA
p54aSAPK
JNK2ALPHA
·
WB
Western blot analysis using JNK2 antibody against PANC-1(1), MCF-7(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using JNK2 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of CAL-27 cells using RXRA antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |