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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-BRG1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SMARCA4
Gene Synonyms
BRG1
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Gene Full Name
SWI/SNF related, matrix associated, actin
dependent regulator of chromatin, subfamily a, member 4
Gene Summary
The protein encoded by this gene is a
member of the SWI/SNF family of proteins and is similar to the brahma protein
of Drosophila. Members of this family have helicase and ATPase activities and
are thought to regulate transcription of certain genes by altering the
chromatin structure around those genes. The encoded protein is part of the
large ATP-dependent chromatin remodeling complex SNF/SWI, which is required
for transcriptional activation of genes normally repressed by chromatin. In
addition, this protein can bind BRCA1, as well as regulate the expression of
the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor
predisposition syndrome type 2. Multiple transcript variants encoding
different isoforms have been found for this gene.
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Molecular
Weight(MW)
185 kDa
Cellular
Localizatio
Nucleus
Application
IHC:1:200-1:1000
CSS4
SNF2
SWI2
MRD16
RTPS2
BAF190
SNF2L4
SNF2LB
hSNF2b
BAF190A
SNF2-beta
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WB
Western blot analysis using BRG1 antibody against Jurkat(1), COS7(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using BRG1 antibody with DAB staining.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |