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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-XRN1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
XRN1
Gene Synonyms
SEP1
Gene Full Name
5'-3' exoribonuclease 1
Gene Summary
This gene encodes a member of the 5'-3'
exonuclease family. The encoded protein may be involved in
replication-dependent histone mRNA degradation, and interacts directly with
the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a
similar protein in yeast has been implicated in a variety of nuclear and
cytoplasmic functions, including homologous recombination, meiosis, telomere
maintenance, and microtubule assembly. Mutations in this gene are associated
with osteosarcoma, suggesting that the encoded protein may also play a role
in bone formation. Alternative splicing results in multiple transcript
variants.
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Molecular
Weight(MW)
194 kDa
Cellular
Localizatio
Cytoplasm
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
·
WB
Western blot analysis using XRN1 antibody against MCF-7(1)cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using XRN1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of A549 cells using XRN1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |