Product Profile

Product Name	Anti-FTH1 antibody
Antibody Type	Primary Antibodies
Immunogen	Polypeptide

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	FTH1
Gene Synonyms	FHC FTH HFE5 PLIF FTHL6 PIG15 Hide
Gene Full Name	ferritin heavy chain 1
Gene Summary	s gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	21 kDa（Observed:42 kDa）
Cellular Localizatio	Cytoplasm, Nucleus

Application

·

WB

Western blot analysis using FTH1 antibody against HepG2(1), Jurkat(2), Hela(3), A549(4) cell lysate.

·

IHC

Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using FTH1 antibody with DAB staining.

·

ICC/IF

Immunofluorescence analysis of MG-63 cells using FTH1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.

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