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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-PTPN11 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PTPN11
Gene Synonyms
CFC
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Gene Full Name
protein tyrosine phosphatase non-receptor
type 11
Gene Summary
The protein encoded by this gene is a
member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be
signaling molecules that regulate a variety of cellular processes including
cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains, which function as
phospho-tyrosine binding domains and mediate the interaction of this PTP with
its substrates. This PTP is widely expressed in most tissues and plays a
regulatory role in various cell signaling events that are important for a
diversity of cell functions, such as mitogenic activation, metabolic control,
transcription regulation, and cell migration. Mutations in this gene are a
cause of Noonan syndrome as well as acute myeloid leukemia. [provided by
RefSeq, Aug 2016]
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Molecular
Weight(MW)
68 kDa
Cellular
Localizatio
Cytoplasm, Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
NS1
JMML
SHP2
BPTP3
PTP2C
METCDS
PTP-1D
SH-PTP2
SH-PTP3
·
WB
Western blot analysis using PTPN11 antibody against HepG2(1),THP-1(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using PTPN11 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using PTPN11 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |