Product Profile

Product Name	Anti-CHRNB1 antibody
Antibody Type	Primary Antibodies
Immunogen	recombinant protein

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Application	ELISAICC/IFIHCWB
	WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	CHRNB1
Gene Synonyms	ACHRB CHRNB CMS1D CMS2A CMS2C SCCMS Hide
Gene Full Name	cholinergic receptor nicotinic beta 1 subunit
Gene Summary	The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008] Hide
Molecular Weight(MW)	57 kDa
Cellular Localizatio	Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse

Application

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WB

Western blot analysis using CHRNB1 antibody against A431(1) cell lysate.

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IHC

Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using CHRNB1 antibody with DAB staining.

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ICC/IF

Immunofluorescence analysis of MG-63 cells using CHRNB1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes

WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500

Additional Information

Form	Liquid
Storage Instruction	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.