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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-MDM2 antibody
Antibody Type
Primary Antibodies
Immunogen
recombinant
protein
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
MDM2
Gene Synonyms
HDMX
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Gene Full Name
MDM2 proto-oncogene
Gene Summary
This gene encodes a nuclear-localized E3
ubiquitin ligase. The encoded protein can promote tumor formation by
targeting tumor suppressor proteins, such as p53, for proteasomal
degradation. This gene is itself transcriptionally-regulated by p53.
Overexpression or amplification of this locus is detected in a variety of
different cancers. There is a pseudogene for this gene on chromosome 2.
Alternative splicing results in a multitude of transcript variants, many of
which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
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Molecular
Weight(MW)
55 kDa(Observed: 80
kDa)
Cellular
Localizatio
Cytoplasm, Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
LSKB
hdm2
ACTFS
·
WB
Western blot analysis using MDM2 antibody against HEK293(1) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using MDM2 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using MDM2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |