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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-ABCG2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ABCG2
Gene Synonyms
MRX
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Gene Full Name
ATP binding cassette subfamily G member 2
(Junior blood group)
Gene Summary
The membrane-associated protein encoded
by this gene is included in the superfamily of ATP-binding cassette (ABC)
transporters. ABC proteins transport various molecules across extra- and
intra-cellular membranes. ABC genes are divided into seven distinct subfamilies
(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of
the White subfamily. Alternatively referred to as a breast cancer resistance
protein, this protein functions as a xenobiotic transporter which may play a
major role in multi-drug resistance. It likely serves as a cellular defense
mechanism in response to mitoxantrone and anthracycline exposure. Significant
expression of this protein has been observed in the placenta, which may
suggest a potential role for this molecule in placenta tissue. Multiple
transcript variants encoding different isoforms have been found for this
gene. [provided by RefSeq, Apr 2012]
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Molecular
Weight(MW)
72 kDa, 67 kDa(Observed:140 kDa Homodimer)
Cellular
Localizatio
Cell membrane, Membrane, Mitochondrion
Application
IHC:1:200-1:1000
MXR
ABCP
BCRP
BMDP
MXR1
ABC15
BCRP1
CD338
GOUT1
MXR-1
CDw338
UAQTL1
EST157481
·
WB
Western blot analysis using ABCG2 antibody against Hela(1), A431(2), HepG2(3) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using ABCG2 antibody with DAB staining.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |