|
- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：OM641708
- 发布日期： 2024-09-02
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
TP2A
TOPIIA
TOP2alpha
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
·
IHC
Immunohistochemical
analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB
staining.
·
ICC/IF
Immunofluorescence
analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-TOP2A antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHC
IHC:1:200-1:1000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
TOP2A
Gene Synonyms
TOP2
Hide
Gene Full Name
DNA topoisomerase II alpha
Gene Summary
This gene encodes a DNA topoisomerase, an
enzyme that controls and alters the topologic states of DNA during
transcription. This nuclear enzyme is involved in processes such as
chromosome condensation, chromatid separation, and the relief of torsional stress
that occurs during DNA transcription and replication. It catalyzes the
transient breaking and rejoining of two strands of duplex DNA which allows
the strands to pass through one another, thus altering the topology of DNA.
Two forms of this enzyme exist as likely products of a gene duplication
event. The gene encoding this form, alpha, is localized to chromosome 17 and
the beta gene is localized to chromosome 3. The gene encoding this enzyme
functions as the target for several anticancer agents and a variety of
mutations in this gene have been associated with the development of drug
resistance. Reduced activity of this enzyme may also play a role in
ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
Hide
Cellular Localizatio
Cytoplasm, Nucleus
Application
ICC/IF:1:100-1:500
TP2A
TOPIIA
TOP2alpha
·
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using TOP2A antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using TOP2A antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
IHC:1:200-1:1000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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