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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-SERCA2 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ATP2A2
Gene Synonyms
DD
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Gene Full Name
ATPase sarcoplasmic/endoplasmic reticulum
Ca2+ transporting 2
Gene Summary
This gene encodes one of the SERCA
Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or
endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the
hydrolysis of ATP coupled with the translocation of calcium from the cytosol
into the sarcoplasmic reticulum lumen, and is involved in regulation of the
contraction/relaxation cycle. Mutations in this gene cause Darier-White
disease, also known as keratosis follicularis, an autosomal dominant skin
disorder characterized by loss of adhesion between epidermal cells and
abnormal keratinization. Other types of mutations in this gene have been
associated with various forms of muscular dystrophies. Alternative splicing
results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Dec 2019]
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Molecular
Weight(MW)
115 kDa
Cellular
Localizatio
Endoplasmic reticulum, Membrane,
Sarcoplasmic reticulum
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
DAR
ATP2B
SERCA2
·
WB
Western blot analysis using SERCA2 antibody against A431(1),MCF-1(2),Hela(4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded renal carcinoma tissues using SERCA2 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using SERCA2 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |