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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-LXR alpha antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
NR1H3
Gene Synonyms
LXRA
Gene Full Name
nuclear receptor subfamily 1 group H
member 3
Gene Summary
The protein encoded by this gene belongs
to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family
members are key regulators of macrophage function, controlling transcriptional
programs involved in lipid homeostasis and inflammation. This protein is
highly expressed in visceral organs, including liver, kidney and intestine.
It forms a heterodimer with retinoid X receptor (RXR), and regulates
expression of target genes containing retinoid response elements. Studies in
mice lacking this gene suggest that it may play an important role in the
regulation of cholesterol homeostasis. Alternatively spliced transcript
variants encoding different isoforms have been found for this gene. [provided
by RefSeq, Oct 2011]
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Molecular
Weight(MW)
50 kDa
Cellular
Localizatio
Cytoplasm, Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
LXR-a
RLD-1
·
WB
Western blot analysis using LXR alpha antibody against A431(1),Raji(2),HepG2(3) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using LXR alpha antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of SK-OV-3 cells using LXR alpha antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |