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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-Caldesmon antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
CALD1
Gene Synonyms
CDM
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Gene Full Name
caldesmon 1
Gene Summary
This gene encodes a calmodulin- and
actin-binding protein that plays an essential role in the regulation of
smooth muscle and nonmuscle contraction. The conserved domain of this protein
possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin,
myosin, and phospholipids. This protein is a potent inhibitor of the
actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor
for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative
splicing of this gene results in multiple transcript variants encoding
distinct isoforms. [provided by RefSeq, Jul 2008]
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Molecular
Weight(MW)
93 kDa
Cellular
Localizatio
Cytoplasm, Cytoskeleton
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
HCAD
LCAD
H-CAD
L-CAD
NAG22
·
WB
Western blot analysis using Caldesmon antibody against A431(1), COS-7(2), MCF-7(3) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using Caldesmon antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of SK-OV-3 cells using Caldesmon antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |