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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-YB1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
YBX1
Gene Synonyms
YB1
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Gene Full Name
Y-box binding protein 1
Gene Summary
This gene encodes a highly conserved cold
shock domain protein that has broad nucleic acid binding properties. The
encoded protein functions as both a DNA and RNA binding protein and has been
implicated in numerous cellular processes including regulation of
transcription and translation, pre-mRNA splicing, DNA reparation and mRNA
packaging. This protein is also a component of messenger ribonucleoprotein
(mRNP) complexes and may have a role in microRNA processing. This protein can
be secreted through non-classical pathways and functions as an extracellular
mitogen. Aberrant expression of the gene is associated with cancer
proliferation in numerous tissues. This gene may be a prognostic marker for
poor outcome and drug resistance in certain cancers. Alternate splicing
results in multiple transcript variants. Pseudogenes of this gene are found
on multiple chromosomes. [provided by RefSeq, Sep 2015]
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Molecular
Weight(MW)
36 kDa
Cellular
Localizatio
Cytoplasm, Nucleus, Secreted
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
BP-8
CSDB
DBPB
YB-1
CBF-A
CSDA2
EFI-A
NSEP1
NSEP-1
MDR-NF1
·
WB
Western blot analysis using YB1 antibody against THP-1(1), HA431(2, Raji(3), HepG2(4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using YB1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of SK-OV-3 cells using YB1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |