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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-Integrin alphaV antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ITGAV
Gene Synonyms
CD51
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Gene Full Name
integrin subunit alpha V
Gene Summary
The product of this gene belongs to the
integrin alpha chain family. Integrins are heterodimeric integral membrane
proteins composed of an alpha subunit and a beta subunit that function in
cell surface adhesion and signaling. The encoded preproprotein is proteolytically
processed to generate light and heavy chains that comprise the alpha V
subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta
8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also
known as the vitronectin receptor. This integrin may regulate angiogenesis
and cancer progression. Alternative splicing results in multiple transcript
variants. Note that the integrin alpha 5 and integrin alpha V subunits are
encoded by distinct genes. [provided by RefSeq, Oct 2015]
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Molecular
Weight(MW)
116 kDa
Cellular
Localizatio
Membrane
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
MSK8
VNRA
VTNR
·
WB
Western blot analysis using Integrin alphaV antibody against PC-12(1), NIH/3T3(2), Hela(3), A431(4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded renal carcinoma tissues using Integrin alphaV antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using Integrin alphaV antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |