|
- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：OM641708
- 发布日期： 2024-08-30
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-SPHK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SPHK1
Gene Synonyms
SPHK
Gene Full Name
sphingosine kinase 1
Gene Summary
The protein encoded by this gene
catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate
(S1P), a lipid mediator with both intra- and extracellular functions.
Intracellularly, S1P regulates proliferation and survival, and extracellularly,
it is a ligand for cell surface G protein-coupled receptors. This protein,
and its product S1P, play a key role in TNF-alpha signaling and the
NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and
immune processes. Phosphorylation of this protein alters its catalytic
activity and promotes its translocation to the plasma membrane. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Sep 2017]
Hide
Molecular
Weight(MW)
43 kDa
Cellular
Localizatio
Cell junction, Cell membrane, Coated pit,
Cytoplasm, Endosome, Membrane, Nucleus, Synapse
Application
·
WB
Western blot
analysis using SPHK1 antibody against HEK293(1), L-02(2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using SPHK1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using SPHK1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-SPHK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SPHK1
Gene Synonyms
SPHK
Gene Full Name
sphingosine kinase 1
Gene Summary
The protein encoded by this gene
catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate
(S1P), a lipid mediator with both intra- and extracellular functions.
Intracellularly, S1P regulates proliferation and survival, and extracellularly,
it is a ligand for cell surface G protein-coupled receptors. This protein,
and its product S1P, play a key role in TNF-alpha signaling and the
NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and
immune processes. Phosphorylation of this protein alters its catalytic
activity and promotes its translocation to the plasma membrane. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Sep 2017]
Hide
Molecular
Weight(MW)
43 kDa
Cellular
Localizatio
Cell junction, Cell membrane, Coated pit,
Cytoplasm, Endosome, Membrane, Nucleus, Synapse
Application
·
WB
Western blot
analysis using SPHK1 antibody against HEK293(1), L-02(2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using SPHK1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using SPHK1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-SPHK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SPHK1
Gene Synonyms
SPHK
Gene Full Name
sphingosine kinase 1
Gene Summary
The protein encoded by this gene
catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate
(S1P), a lipid mediator with both intra- and extracellular functions.
Intracellularly, S1P regulates proliferation and survival, and extracellularly,
it is a ligand for cell surface G protein-coupled receptors. This protein,
and its product S1P, play a key role in TNF-alpha signaling and the
NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and
immune processes. Phosphorylation of this protein alters its catalytic
activity and promotes its translocation to the plasma membrane. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Sep 2017]
Hide
Molecular
Weight(MW)
43 kDa
Cellular
Localizatio
Cell junction, Cell membrane, Coated pit,
Cytoplasm, Endosome, Membrane, Nucleus, Synapse
Application
·
WB
Western blot
analysis using SPHK1 antibody against HEK293(1), L-02(2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using SPHK1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using SPHK1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-SPHK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SPHK1
Gene Synonyms
SPHK
Gene Full Name
sphingosine kinase 1
Gene Summary
The protein encoded by this gene
catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate
(S1P), a lipid mediator with both intra- and extracellular functions.
Intracellularly, S1P regulates proliferation and survival, and extracellularly,
it is a ligand for cell surface G protein-coupled receptors. This protein,
and its product S1P, play a key role in TNF-alpha signaling and the
NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and
immune processes. Phosphorylation of this protein alters its catalytic
activity and promotes its translocation to the plasma membrane. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Sep 2017]
Hide
Molecular
Weight(MW)
43 kDa
Cellular
Localizatio
Cell junction, Cell membrane, Coated pit,
Cytoplasm, Endosome, Membrane, Nucleus, Synapse
Application
·
WB
Western blot
analysis using SPHK1 antibody against HEK293(1), L-02(2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using SPHK1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using SPHK1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-SPHK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SPHK1
Gene Synonyms
SPHK
Gene Full Name
sphingosine kinase 1
Gene Summary
The protein encoded by this gene
catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate
(S1P), a lipid mediator with both intra- and extracellular functions.
Intracellularly, S1P regulates proliferation and survival, and extracellularly,
it is a ligand for cell surface G protein-coupled receptors. This protein,
and its product S1P, play a key role in TNF-alpha signaling and the
NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and
immune processes. Phosphorylation of this protein alters its catalytic
activity and promotes its translocation to the plasma membrane. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Sep 2017]
Hide
Molecular
Weight(MW)
43 kDa
Cellular
Localizatio
Cell junction, Cell membrane, Coated pit,
Cytoplasm, Endosome, Membrane, Nucleus, Synapse
Application
·
WB
Western blot
analysis using SPHK1 antibody against HEK293(1), L-02(2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using SPHK1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using SPHK1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-SPHK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SPHK1
Gene Synonyms
SPHK
Gene Full Name
sphingosine kinase 1
Gene Summary
The protein encoded by this gene
catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate
(S1P), a lipid mediator with both intra- and extracellular functions.
Intracellularly, S1P regulates proliferation and survival, and extracellularly,
it is a ligand for cell surface G protein-coupled receptors. This protein,
and its product S1P, play a key role in TNF-alpha signaling and the
NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and
immune processes. Phosphorylation of this protein alters its catalytic
activity and promotes its translocation to the plasma membrane. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Sep 2017]
Hide
Molecular
Weight(MW)
43 kDa
Cellular
Localizatio
Cell junction, Cell membrane, Coated pit,
Cytoplasm, Endosome, Membrane, Nucleus, Synapse
Application
·
WB
Western blot
analysis using SPHK1 antibody against HEK293(1), L-02(2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using SPHK1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using SPHK1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-SPHK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SPHK1
Gene Synonyms
SPHK
Gene Full Name
sphingosine kinase 1
Gene Summary
The protein encoded by this gene
catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate
(S1P), a lipid mediator with both intra- and extracellular functions.
Intracellularly, S1P regulates proliferation and survival, and extracellularly,
it is a ligand for cell surface G protein-coupled receptors. This protein,
and its product S1P, play a key role in TNF-alpha signaling and the
NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and
immune processes. Phosphorylation of this protein alters its catalytic
activity and promotes its translocation to the plasma membrane. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Sep 2017]
Hide
Molecular
Weight(MW)
43 kDa
Cellular
Localizatio
Cell junction, Cell membrane, Coated pit,
Cytoplasm, Endosome, Membrane, Nucleus, Synapse
Application
·
WB
Western blot
analysis using SPHK1 antibody against HEK293(1), L-02(2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using SPHK1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using SPHK1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-SPHK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SPHK1
Gene Synonyms
SPHK
Gene Full Name
sphingosine kinase 1
Gene Summary
The protein encoded by this gene
catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate
(S1P), a lipid mediator with both intra- and extracellular functions.
Intracellularly, S1P regulates proliferation and survival, and extracellularly,
it is a ligand for cell surface G protein-coupled receptors. This protein,
and its product S1P, play a key role in TNF-alpha signaling and the
NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and
immune processes. Phosphorylation of this protein alters its catalytic
activity and promotes its translocation to the plasma membrane. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Sep 2017]
Hide
Molecular
Weight(MW)
43 kDa
Cellular
Localizatio
Cell junction, Cell membrane, Coated pit,
Cytoplasm, Endosome, Membrane, Nucleus, Synapse
Application
·
WB
Western blot
analysis using SPHK1 antibody against HEK293(1), L-02(2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using SPHK1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using SPHK1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-SPHK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SPHK1
Gene Synonyms
SPHK
Gene Full Name
sphingosine kinase 1
Gene Summary
The protein encoded by this gene
catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate
(S1P), a lipid mediator with both intra- and extracellular functions.
Intracellularly, S1P regulates proliferation and survival, and extracellularly,
it is a ligand for cell surface G protein-coupled receptors. This protein,
and its product S1P, play a key role in TNF-alpha signaling and the
NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and
immune processes. Phosphorylation of this protein alters its catalytic
activity and promotes its translocation to the plasma membrane. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Sep 2017]
Hide
Molecular
Weight(MW)
43 kDa
Cellular
Localizatio
Cell junction, Cell membrane, Coated pit,
Cytoplasm, Endosome, Membrane, Nucleus, Synapse
Application
·
WB
Western blot
analysis using SPHK1 antibody against HEK293(1), L-02(2) cell lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using SPHK1 antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of SK-OV-3 cells using SPHK1 antibody (green). Blue: DAPI fluorescent
DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555
phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-SPHK1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
SPHK1
Gene Synonyms
SPHK
Gene Full Name
sphingosine kinase 1
Gene Summary
The protein encoded by this gene
catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate
(S1P), a lipid mediator with both intra- and extracellular functions.
Intracellularly, S1P regulates proliferation and survival, and extracellularly,
it is a ligand for cell surface G protein-coupled receptors. This protein,
and its product S1P, play a key role in TNF-alpha signaling and the
NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and
immune processes. Phosphorylation of this protein alters its catalytic
activity and promotes its translocation to the plasma membrane. Alternative
splicing results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Sep 2017]
Hide
Molecular
Weight(MW)
43 kDa
Cellular
Localizatio
Cell junction, Cell membrane, Coated pit,
Cytoplasm, Endosome, Membrane, Nucleus, Synapse
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
·
WB
Western blot analysis using SPHK1 antibody against HEK293(1), L-02(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using SPHK1 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of SK-OV-3 cells using SPHK1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
-
中秋迎好礼 中秋迎好礼 随着国产3A大作《黑神话：悟空》的面世，现我司推出活动。 从即日起至2024年9月18日，购买ELISA试剂盒满五盒，即可申领《黑神话：悟空》数字标准版兑换码。 ... VIEW DETAILS
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