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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-Integrin alpha6 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
ITGA6
Gene Synonyms
CD49f
Gene Full Name
integrin subunit alpha 6
Gene Summary
The gene encodes a member of the integrin
alpha chain family of proteins. Integrins are heterodimeric integral membrane
proteins composed of an alpha chain and a beta chain that function in cell
surface adhesion and signaling. The encoded preproprotein is proteolytically
processed to generate light and heavy chains that comprise the alpha 6
subunit. This subunit may associate with a beta 1 or beta 4 subunit to form
an integrin that interacts with extracellular matrix proteins including
members of the laminin family. The alpha 6 beta 4 integrin may promote
tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate
erbB2/HER2 signaling. Alternative splicing results in multiple transcript
variants. [provided by RefSeq, Oct 2015]
More
Molecular
Weight(MW)
127 kDa
Cellular
Localizatio
Cell membrane, Membrane
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
VLA-6
ITGA6B
·
WB
Western blot analysis using Integrin alpha6 antibody against THp-1(1), Raji(2), COS-7(3) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using Integrin alpha6 antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of MG-63 cells using Integrin alpha6 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |