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产地 | 上海 |
品牌 | OminimAbs |
保存条件 | |
货号 | OM641708 |
用途 | 实验研究 |
应用范围 | 科研实验 |
抗原来源 | 电询 |
保质期 | 2年 |
抗体名 | 电询 |
是否单克隆 | 否 |
克隆性 | 否 |
靶点 | 电询 |
适应物种 | 电询 |
形态 | 电询 |
宿主 | 电询 |
标记物 | 电询 |
包装规格 | 毫升 |
亚型 | 电询 |
标识物 | 电询 |
浓度 | 电询% |
免疫原 | 电询 |
是否进口 | 否 |
Product Profile
Product Name
Anti-PKC epsilon antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
PRKCE
Gene Synonyms
PKCE
Gene Full Name
protein kinase C epsilon
Gene Summary
Protein kinase C (PKC) is a family of
serine- and threonine-specific protein kinases that can be activated by
calcium and the second messenger diacylglycerol. PKC family members
phosphorylate a wide variety of protein targets and are known to be involved
in diverse cellular signaling pathways. PKC family members also serve as
major receptors for phorbol esters, a class of tumor promoters. Each member
of the PKC family has a specific expression profile and is believed to play a
distinct role in cells. The protein encoded by this gene is one of the PKC
family members. This kinase has been shown to be involved in many different
cellular functions, such as neuron channel activation, apoptosis,
cardioprotection from ischemia, heat shock response, as well as insulin
exocytosis. Knockout studies in mice suggest that this kinase is important
for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and
may also play a role in controlling anxiety-like behavior. [provided by
RefSeq, Jul 2008]
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Molecular
Weight(MW)
84 kDa
Cellular
Localizatio
Cell membrane, Cytoplasm, Cytoskeleton,
Membrane, Nucleus
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
nPKC-epsilon
·
WB
Western blot analysis using PKC epsilon antibody against Jurkat(1), Hela(2) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using PKC epsilon antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using PKC epsilon antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application Notes |
WB:1:200-1:2000 |
Additional Information
Form |
Liquid |
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |