|
- 品牌：OminimAbs
- 产地：上海
- 型号：毫升
- 货号：OM641708
- 发布日期： 2024-08-29
- 更新日期： 2024-10-09
| 产地 | 上海 |
| 品牌 | OminimAbs |
| 保存条件 | |
| 货号 | OM641708 |
| 用途 | 实验研究 |
| 应用范围 | 科研实验 |
| 抗原来源 | 电询 |
| 保质期 | 2年 |
| 抗体名 | 电询 |
| 是否单克隆 | 否 |
| 克隆性 | 否 |
| 靶点 | 电询 |
| 适应物种 | 电询 |
| 形态 | 电询 |
| 宿主 | 电询 |
| 标记物 | 电询 |
| 包装规格 | 毫升 |
| 亚型 | 电询 |
| 标识物 | 电询 |
| 浓度 | 电询% |
| 免疫原 | 电询 |
| 是否进口 | 否 |
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
Hide
Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
Hide
Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
·
WB
Western blot
analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell
lysate.
· 
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
Hide
Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
Hide
Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
·
WB
Western blot
analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell
lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
Hide
Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
Hide
Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
·
WB
Western blot
analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell
lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
Hide
Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
Hide
Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
·
WB
Western blot
analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell
lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
Hide
Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
Hide
Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
·
WB
Western blot
analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell
lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
Hide
Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
Hide
Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
·
WB
Western blot
analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell
lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
Hide
Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
Hide
Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
·
WB
Western blot
analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell
lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
Hide
Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
Hide
Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
·
WB
Western blot
analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell
lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
Hide
Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
Hide
Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
·
WB
Western blot
analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell
lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
Hide
Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
Hide
Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
·
WB
Western blot
analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell
lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
Hide
Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
Hide
Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
·
WB
Western blot
analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell
lysate.
·
IHC
Immunohistochemical
analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with
DAB staining.
·
ICC/IF
Immunofluorescence
analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA
dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Application
Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage
Instruction
Shipped at 4°C. Store at +4°C short term
(1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05%
sodium azide.
Product Profile
Product Name
Anti-HTR2C antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested
Application
ELISAICC/IFIHCWB
WB:1:200-1:2000
Species
Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Protein A
Target Information
Gene Symbol
HTR2C
Gene Synonyms
HTR1C
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Gene Full Name
5-hydroxytryptamine receptor 2C
Gene Summary
This gene encodes a seven-transmembrane
G-protein-coupled receptor. The encoded protein responds to signaling through
the neurotransmitter serotonin. The mRNA of this gene is subject to multiple
RNA editing events, where adenosine residues encoded by the genome are
converted to inosines. RNA editing is predicted to alter the structure of the
second intracellular loop, thereby generating alternate protein forms with
decreased ability to interact with G proteins. Abnormalities in RNA editing
of this gene have been detected in victims of suicide that suffer from
depression. In addition, naturally-occuring variation in the promoter and 5'
non-coding and coding regions of this gene may show statistically-significant
association with mental illness and behavioral disorders. Alternative
splicing results in multiple different transcript variants. [provided by
RefSeq, Jan 2015]
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Molecular
Weight(MW)
52 kDa
Cellular
Localizatio
Cell membrane
Application
IHC:1:200-1:1000
ICC/IF:1:100-1:500
5-HT1C
5-HT2C
5HTR2C
5-HTR2C
·
WB
Western blot analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell lysate.
·
IHC
Immunohistochemical analysis of paraffin-embedded breast cancer tissues using HTR2C antibody with DAB staining.
·
ICC/IF
Immunofluorescence analysis of Hela cells using HTR2C antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
|
Application Notes |
WB:1:200-1:2000 |
Additional Information
|
Form |
Liquid |
|
Storage Instruction |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
|
Storage Buffer |
Purified antibody in PBS with 0.05% sodium azide. |
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